Gold(<scp>i</scp>)-catalyzed diastereo- and enantioselective [4 + 3] cycloadditions: construction of functionalized furano-benzoxepins-Reference-Cited by-同舟云学术

Gold(i)-catalyzed diastereo- and enantioselective [4 + 3] cycloadditions: construction of functionalized furano-benzoxepins

Published:2022 Issue:19 Volume:9 Page:5292-5298
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Xunhua¹,Lv Ruifeng¹,Li Xiaoxun¹²^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China

2. Suzhou Research Institute, Shandong University, Suzhou, Jiangsu 215123, China

Abstract

Highly diastereo- and enantioselective [4 + 3] cycloadditions of 2-(1-alkynyl)-2-alken-1-ones with o-QMs have been realized via a simple chiral gold catalysis, providing facile access to various functionalized furano-benzoxepins.

Funder

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Shandong University

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO01070D

Reference66 articles.