Confirmation of the cellular targets of benomyl and rapamycin using next-generation sequencing of resistant mutants in S. cerevisiae-Reference-Cited by-同舟云学术

Confirmation of the cellular targets of benomyl and rapamycin using next-generation sequencing of resistant mutants in S. cerevisiae

Published:2014 Issue:12 Volume:10 Page:3179-3187
ISSN:1742-206X
Container-title:Mol. BioSyst.
language:en
Short-container-title:Mol. BioSyst.

Author:

Wride Dustin A.¹²³,Pourmand Nader⁴²³,Bray Walter M.⁵²³,Kosarchuk Jacob J.⁵²³,Nisam Sean C.⁵²³,Quan Tiffani K.⁶²³,Berkeley Ray F.¹²³,Katzman Sol⁷²³,Hartzog Grant A.⁶²³,Dobkin Carlos E.⁸²³,Scott Lokey R.¹²³

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of California

3. Santa Cruz, USA

4. Department of Biomolecular Engineering

5. Chemical Screening Center

6. Molecular Cell and Developmental Biology

7. Center for Biomolecular Science and Engineering

8. Department of Economics

Abstract

Demonstrating the use of next generation sequencing (NGS) to identify mutations that confer resistance to benomyl and rapamycin, and a method for mapping these mutations to their known biological targets.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MB/C4MB00146J

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