Novel stilbene scaffolds efficiently target Mycobacterium tuberculosis nucleoid-associated protein, HU

Author:

Peraman Ramalingam1234,Meka Geethavani1234,Chilamakuru Naresh Babu1234,Kutagulla Vinay Kumar1234,Malla Saloni56789,Ashby Charles R.1011129,Tiwari Amit K.56789ORCID,Yiragamreddy Padmanabha Reddy1234

Affiliation:

1. Medicinal chemistry Division

2. Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous

3. Anantapur (AP)

4. India

5. Department of Pharmacology & Experimental Therapeutics

6. College of Pharmacy & Pharmaceutical Sciences

7. The University of Toledo

8. Toledo

9. USA

10. Department of Pharmaceutical Sciences

11. St. John's University

12. Queens

Abstract

Novel scaffolds of stilbene were identified as inhibitors of Mycobacterium tuberculosis by targeting the nucleoid-associated protein, HU, using molecular docking.

Funder

University Grants Commission

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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