Optimizing peptide nucleic acid probes for hybridization-based detection and identification of bacterial pathogens-Reference-Cited by-同舟云学术

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Optimizing peptide nucleic acid probes for hybridization-based detection and identification of bacterial pathogens

Published:2019 Issue:5 Volume:144 Page:1565-1574
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Mach Kathleen E.¹²³⁴⁵^ORCID,Kaushik Aniruddha M.⁶⁷⁸⁴,Hsieh Kuangwen⁶⁷⁸⁴,Wong Pak Kin⁹¹⁰¹¹⁴,Wang Tza-Huei⁶⁷⁸⁴,Liao Joseph C.¹²³⁴⁵

Affiliation:

1. Department of Urology

2. Stanford University School of Medicine

3. Stanford

4. USA

5. Veterans Affairs Palo Alto Health Care System

6. Departments of Mechanical Engineering and Biomedical Engineering

7. Johns Hopkins University

8. Baltimore

9. Department of Biomedical Engineering

10. The Pennsylvania State University

11. University Park

Abstract

Double stranded PNA probes provide improved sensitivity and specificity over PNA beacons for molecular identification of pathogens.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C8AN02194E

Reference56 articles.

1. Clinical and economic evaluation of the impact of rapid microbiological diagnostic testing

2. A Retrospective Study of the Impact of Rapid Diagnostic Testing on Time to Pathogen Identification and Antibiotic Use for Children with Positive Blood Cultures

3. Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia

4. Advances in rapid identification and susceptibility testing of bacteria in the clinical microbiology laboratory: implications for patient care and antimicrobial stewardship programs

5. Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group

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