“Clickable PEG” via anionic copolymerization of ethylene oxide and glycidyl propargyl ether
Author:
Affiliation:
1. Institute of Organic Chemistry
2. Johannes Gutenberg University Mainz
3. D-55128 Mainz
4. Germany
5. Graduate School Materials Science in Mainz
Abstract
First one-step synthesis of poly(ethylene glycol) bearing multiple alkyne-groups along the polyether backbone and subsequent generation of PEG-glycopolymers by CuAAC.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2017/PY/C7PY00173H
Reference37 articles.
1. Polymerization of Ethylene Oxide, Propylene Oxide, and Other Alkylene Oxides: Synthesis, Novel Polymer Architectures, and Bioconjugation
2. Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
3. FDA-approved poly(ethylene glycol)–protein conjugate drugs
4. State of the art in PEGylation: The great versatility achieved after forty years of research
5. Synthesis and applications of heterobifunctional poly(ethylene oxide) oligomers
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