Intracellular calcium dynamics of lymphatic endothelial and muscle cells co-cultured in a Lymphangion-Chip under pulsatile flow-Reference-Cited by-同舟云学术

Intracellular calcium dynamics of lymphatic endothelial and muscle cells co-cultured in a Lymphangion-Chip under pulsatile flow

Published:2022 Issue:13 Volume:147 Page:2953-2965
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Selahi Amirali¹^ORCID,Chakraborty Sanjukta²,Muthuchamy Mariappan²,Zawieja David C.²,Jain Abhishek¹²³^ORCID

Affiliation:

1. Department of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA

2. Department of Medical Physiology, College of Medicine, Texas A&M Health Science Center, Bryan, TX, USA

3. Department of Cardiovascular Sciences, Houston Methodist Academic Institute, Houston, TX, USA

Abstract

A Lymphangion-Chip consisting an endothelial lumen co-cultured with muscle cells was exposed to step or pulsatile flow. The real-time analyses of intracellular calcium dynamics reveal the coupling of signaling between these cells under complex flows.

Funder

National Institute of Biomedical Imaging and Bioengineering

College of Engineering, Texas A and M University

Texas A and M University

American Heart Association

Cancer Prevention and Research Institute of Texas

National Heart, Lung, and Blood Institute

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry