A nanoscale polymolybdate built by two hexavacant Keggin-type fragments via a novel {Ca6P6O38} cluster with β-sheet conformation modulation ability-Reference-Cited by-同舟云学术

A nanoscale polymolybdate built by two hexavacant Keggin-type fragments via a novel {Ca₆P₆O₃₈} cluster with β-sheet conformation modulation ability

Published:2022 Issue:17 Volume:24 Page:3153-3159
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Hua Jiai¹^ORCID,Wei Xueman²,Bian Yujian¹,Ma Xiang¹³^ORCID,Hao Li⁴,Sun Jierui¹,Fan Jingjing¹,Niu Yulan⁴,Wang Yanqing⁵

Affiliation:

1. Department of Chemistry and Chemical Engineering, Taiyuan Institute of Technology, Taiyuan 030008, P. R. China

2. Department of Geriatrics, First affiliated Hospital of Naval Medical University, Shanghai, 200081, P. R. China

3. State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing, 210023, P. R. China

4. Laboratory of Biochemistry and Pharmacy, Taiyuan Institute of Technology, Taiyuan, 030008, P. R. China

5. School of Chemistry and Environmental Engineering, Yancheng Teachers University, Yancheng City, 224007, P. R. China

Abstract

A novel sandwich-type phosphomolybdate based on two hexavacant Keggin-type fragment incorporating a hexagonal calcium phosphorus oxygen cluster {Ca6P6O38} was obtained. It can modulate the β-sheet-rich aggregates of Aβ and thus suppress the ROS produced by those toxic species.

Funder

National Natural Science Foundation of China

Shanxi Province Science Foundation for Youths

State Key Laboratory of Coordination Chemistry

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CE/D2CE00215A

Reference55 articles.

1. Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins