Design, synthesis, antimicrobial, antibiofilm evaluation and Z/E-isomerization of novel 6-((arylamino)methylene)benzo[a] phenazin-5(6H)-ones induced by organic solvent

Author:

Olyaei Abolfazl1ORCID,Ghaleghovandi Nooshin1,Moghadami Foozieh2,Sadeghpour Mahdieh3ORCID,Abediha Shohreh1

Affiliation:

1. Department of Chemistry, Payame Noor University (PNU), PO BOX 19395-4697, Tehran, Iran

2. Department of Biology, Payame Noor University, Tehran, Iran

3. Department of Chemistry, Islamic Azad University, Qazvin Branch, Qazvin, Iran

Abstract

New 6-((arylamino)methylene)benzo[a]phenazin-5(6H)-one derivatives were synthesized, and good yields were achieved through one-pot condensation of 2-hydroxy-1,4-naphthoquinone, 1,2-phenylenediamine, aromatic amines and triethyl orthoformate using formic acid under solvent-free conditions at 90 °C.

Funder

Islamic Azad University

Payame Noor University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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