RGD-modified dihydrolipoamide dehydrogenase conjugated to titanium dioxide nanoparticles –switchableintegrin-targeted photodynamic treatment of melanoma cells
Author:
Affiliation:
1. The School of Molecular Cell Biology and Biotechnology
2. George S. Wise Faculty of Life Sciences
3. Israel
4. The Department of Human Molecular Genetics and Biochemistry
5. Sackler School of Medicine
6. Tel Aviv University
Abstract
This work presents a UVA switchable integrin-targeted photodynamic therapy in melanoma, composed of an RGD-modified DLDH conjugated to TiO2nanoparticles, with high selectivity towards integrin-expressing cancer cells.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA13777J
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