Genome scanning inspired isolation of reedsmycins A–F, polyene-polyol macrolides from Streptomyces sp. CHQ-64-Reference-Cited by-同舟云学术

Genome scanning inspired isolation of reedsmycins A–F, polyene-polyol macrolides from Streptomyces sp. CHQ-64

Published:2015 Issue:29 Volume:5 Page:22777-22782
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Che Qian¹²³⁴⁵,Li Tong¹²³⁴⁵,Liu Xiaofang¹²³⁴⁵,Yao Tingting¹²³⁴⁵,Li Jing⁶⁴⁵⁷,Gu Qianqun¹²³⁴⁵,Li Dehai¹²³⁴⁵,Li Wenli¹²³⁴⁵,Zhu Tianjiao¹²³⁴⁵

Affiliation:

1. Key Laboratory of Marine Drugs

2. Chinese Ministry of Education

3. School of Medicine and Pharmacy

4. Ocean University of China

5. Qingdao 266003

6. College of Marine Life Sciences

7. People's Republic of China

Abstract

Genome scanning of the reed rhizosphere soil-derived Streptomyces sp. CHQ-64 revealed a partial gene cluster, putatively encoding a polyene-polyol compound. Inspired by this, six new polyene-polyol macrolides, reedsmycins A–F (1–6), were obtained.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA15415K

Reference25 articles.

1. New natural product biosynthetic chemistry discovered by genome mining

2. Discovering new bioactive molecules from microbial sources

3. Hybrid Isoprenoids from a Reeds Rhizosphere Soil Derived Actinomycete Streptomyces sp. CHQ-64

4. Polycyclic Hybrid Isoprenoids from a Reed Rhizosphere Soil Derived Streptomyces sp. CHQ-64

5. Characterization of the Tautomycin Biosynthetic Gene Cluster from Streptomyces spiroverticillatus Unveiling New Insights into Dialkylmaleic Anhydride and Polyketide Biosynthesis

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