Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity-Reference-Cited by-同舟云学术

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Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity

Published:2024 Issue:4 Volume:15 Page:1247-1257
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Crocetti Letizia¹^ORCID,Catarzi Francesca¹,Giovannoni Maria Paola¹,Vergelli Claudia¹,Bartolucci Gianluca¹,Pallecchi Marco¹,Paoli Paola²^ORCID,Rossi Patrizia²^ORCID,Lippi Martina²,Schepetkin Igor A.³,Quinn Mark T.³,Guerrini Gabriella¹

Affiliation:

1. NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy

2. Department of Industrial Engineering, University of Florence, Via Santa Marta 3, 50139 Florence, Italy

3. Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA

Abstract

HNE inhibitors with antiradical properties may be therapeutically beneficial for the treatment of respiratory diseases involving inflammation and oxidative stress.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00736G

Reference50 articles.

1. Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

2. Strategies for the inhibition of serine proteases

3. Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

4. A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications

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