The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, andin vitrocytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes

Author:

Yinhua Deng12341ORCID,Foroughi Mohammad Mehdi56789ORCID,Aramesh-Boroujeni Zahra101112139,Jahani Shohreh1415169ORCID,Peydayesh Mohadesh171815169,Borhani Fariba1920219,Khatami Mehrdad141516922ORCID,Rohani Meysam232415169,Dusek Michal252627,Eigner Vaclav252627

Affiliation:

1. Department of Pharmacy

2. Hunan Provincial People's Hospital

3. Changsha 410005

4. P. R. China

5. Department of Chemistry

6. Kerman Branch

7. Islamic Azad University

8. Kerman

9. Iran

10. Department of Clinical Laboratory

11. AlZahra Hospital

12. Isfahan University of Medical Sciences

13. Isfahan

14. Nanobioelectrochemistry Research Center

15. Bam University of Medical Sciences

16. Bam

17. Clinical Research Center

18. Pastor Educational Hospital

19. Medical Ethics and Law Research Center

20. Shahid Beheshti University of Medical Sciences

21. Tehran

22. Cell Therapy and Regenerative Medicine Comprehensive Center

23. Department of Medicine

24. Medical School

25. Institute of Physics of the Czech Academy of Sciences

26. 18221 Prague 8

27. Czech Republic

Abstract

A new complex of holmium, [Ho(bpy)(H2O)6]Cl3has been synthesized, their DNA/BSA/HSA binding, molecular docking, antibacterial activity and MTT assay of niosome nano-encapsulated are investigated.

Funder

Grantová Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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