Colorimetric detection of influenza A virus using antibody-functionalized gold nanoparticles

Author:

Liu Yuanjian12345,Zhang Linqun12345,Wei Wei12345,Zhao Hongyu6745,Zhou Zhenxian6745,Zhang Yuanjian12345,Liu Songqin12345

Affiliation:

1. Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research

2. School of Chemistry and Chemical Engineering

3. Southeast University

4. Nanjing

5. PR China

6. Central Laboratory

7. The Second Affiliated Hospital of Southeast University

Abstract

A colorimetric immunosensor for IAV based on AuNPs modified with mAb is developed. This assay depends on an ordered AuNPs structure covering the virus surface and can be applied to any viral pathogen by incorporating the appropriate pathogen-specific antibody, giving the proposed method a broad prospect in clinical diagnosis applications.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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