Advanced liquid biopsy technologies for circulating biomarker detection

Author:

Soda Narshone12345ORCID,Rehm Bernd H. A.67284ORCID,Sonar Prashant91011124ORCID,Nguyen Nam-Trung5234ORCID,Shiddiky Muhammad J. A.12345ORCID

Affiliation:

1. School of Environment and Science

2. Griffith University

3. Nathan Campus

4. Australia

5. Queensland Micro- and Nanotechnology Centre (QMNC)

6. Centre for Cell Factories and Biopolymers (CCFB)

7. Griffith Institute for Drug Discovery (GRIDD)

8. Nathan

9. School of Chemistry, Physics and Mechanical Engineering

10. Molecular Design and Synthesis

11. Queensland University of Technology (QUT)

12. Brisbane

Abstract

In this review, we have summarised the biogenesis, biological significance, isolation and detection technologies of four widely known circulating biomarkers namely circulating tumour cells, circulating tumor specific DNA, microRNA, and exosomes.

Funder

Australian Research Council

Griffith University

Department of Foreign Affairs and Trade, Australian Government

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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