Conformational control of the bacterial Clp protease by natural product antibiotics-Reference-Cited by-同舟云学术

Conformational control of the bacterial Clp protease by natural product antibiotics

Published:2017 Issue:7 Volume:34 Page:815-831
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Malik I. T.¹²³⁴^ORCID,Brötz-Oesterhelt H.¹²³⁴^ORCID

Affiliation:

1. Department of Microbial Bioactive Compounds

2. Interfaculty Institute of Microbiology and Infection Medicine

3. University of Tuebingen

4. Germany

Abstract

Natural products targeting the bacterial Clp protease unravel key interfaces for protein–protein–interaction and long-distance conformational control.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NP/C6NP00125D

Reference126 articles.

1. WHO , 2014, ISBN: 978 92 4 156474 8

2. J. O'Neill , AMR Review, 2014, Antimicrobial Resistance: Tackling a Crisis for the Future Health and Wealth of Nations

3. New antibiotics from Nature’s chemical inventory

4. Natural products as a source of drug leads to overcome drug resistance

5. Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

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