Proximity-enhanced synthesis of DNA–peptide–DNA triblock molecules-Reference-Cited by-同舟云学术

Proximity-enhanced synthesis of DNA–peptide–DNA triblock molecules

Published:2022 Issue:25 Volume:58 Page:4044-4047
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

MacCulloch Tara¹²,Novacek Alexandra¹²,Stephanopoulos Nicholas¹²^ORCID

Affiliation:

1. School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA

2. Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA

Abstract

We report a proximity-enhanced method to synthesize a peptide flanked by two different oligonucleotide handles.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC04970D

Reference31 articles.

1. Emerging applications of peptide–oligonucleotide conjugates: bioactive scaffolds, self-assembling systems, and hybrid nanomaterials

2. Oligonucleotide conjugates – Candidates for gene silencing therapeutics

3. Synthetic Nucleic Acid Analogues in Gene Therapy: An Update for Peptide-Oligonucleotide Conjugates

4. Instructing cells with programmable peptide DNA hybrids

5. Self-assembling DNA–peptide hybrids: morphological consequences of oligonucleotide grafting to a pathogenic amyloid fibrils forming dipeptide

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