Late-stage functionalization of 5-nitrofurans derivatives and their antibacterial activities-Reference-Cited by-同舟云学术

Late-stage functionalization of 5-nitrofurans derivatives and their antibacterial activities

Published:2023 Issue:5 Volume:13 Page:3204-3209
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chen Geshuyi¹,Chang Zhe²,Yuan Pei¹,Wang Si²,Yang Yongxiu¹³⁴^ORCID,Liang Xiaolei¹³,Zhao Depeng²^ORCID

Affiliation:

1. The First Clinical Medical College, Lanzhou University, Lanzhou, China

2. Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China

3. The First Clinical Medical College, Lanzhou University. Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Key Laboratory for Gynecologic Oncology, Lanzhou, 730000, Gansu Province, China

4. Lead Contact, China

Abstract

Cu-catalyzed C–H late-stage functionalization were employed to modify 5-nitrofuran drugs. Compound 1 and 18 were the most active among all compounds, and the cell cytotoxicity assays were conducted.

Funder

National Natural Science Foundation of China

Science and Technology Department of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA07676D

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