Trehalose-cored amphiphiles for membrane protein stabilization: importance of the detergent micelle size in GPCR stability-Reference-Cited by-同舟云学术

Trehalose-cored amphiphiles for membrane protein stabilization: importance of the detergent micelle size in GPCR stability

Published:2019 Issue:12 Volume:17 Page:3249-3257
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Das Manabendra¹²³⁴^ORCID,Du Yang⁵⁶⁷⁸^ORCID,Mortensen Jonas S.⁹¹⁰¹¹¹²^ORCID,Ramos Manuel¹³¹⁴¹⁵¹⁶¹⁷,Ghani Lubna¹²³⁴^ORCID,Lee Ho Jin¹²³⁴^ORCID,Bae Hyoung Eun¹²³⁴^ORCID,Byrne Bernadette¹⁸¹⁹²⁰²¹^ORCID,Guan Lan¹³¹⁴¹⁵¹⁶¹⁷^ORCID,Loland Claus J.⁹¹⁰¹¹¹²^ORCID,Kobilka Brian K.⁵⁶⁷⁸^ORCID,Chae Pil Seok¹²³⁴^ORCID

Affiliation:

1. Department of Bionanotechnology

2. Hanyang University

3. Ansan

4. Korea

5. Molecular and Cellular Physiology

6. Stanford University

7. Stanford

8. USA

9. Department of Neuroscience

10. University of Copenhagen

11. Copenhagen

12. Denmark

13. Department of Cell Physiology and Molecular Biophysics

14. Center for Membrane Protein Research

15. School of Medicine

16. Texas Tech University Health Sciences Center

17. Lubbock

18. Department of Life Sciences

19. Imperial College London

20. London

21. SW7 2AZ UK

Abstract

A novel class of non-chromophoric trehalose-cored amphiphiles was developed and some of the detergents displayed favorable behavior in stabilizing membrane proteins.

Funder

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB03153C

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