An unexpected acid-catalyzed decomposition reaction of cilnidipine and pranidipine to the decarboxylative bridged tricyclic products via cascade rearrangements-Reference-Cited by-同舟云学术

An unexpected acid-catalyzed decomposition reaction of cilnidipine and pranidipine to the decarboxylative bridged tricyclic products via cascade rearrangements

Published:2017 Issue:11 Volume:4 Page:2163-2166
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yang Minghua¹²³⁴⁵,Zhang Shusheng⁶⁷⁸⁹⁴,Zhang Xiang¹⁰¹¹¹²⁴,Wang Haoyang⁶⁷⁸⁹⁴,Zhang Fang⁶⁷⁸⁹⁴,Hou Yuting¹²³⁴,Su Yue¹²³⁴,Guo Yinlong⁶⁷⁸⁹⁴^ORCID

Affiliation:

1. Center for Chinese Medicine Therapy and Systems Biology

2. Shanghai University of Traditional Chinese Medicine

3. Shanghai 201203

4. China

5. Shanghai Pudong Institute for Food and Drug Control

6. State Key Laboratory of Organometallic Chemistry and National Center for Organic Mass Spectrometry in Shanghai

7. Shanghai Institute of Organic Chemistry

8. Chinese Academy of Sciences

9. Shanghai 200032

10. Department of Applied Chemistry

11. Zhejiang Gongshang University

12. Hangzhou 310018

Abstract

A gas-phase Carroll rearrangement occurring during electrospray ionization tandem mass spectrometry led to the discovery of bridged tricyclic degradation products from cilnidipine and pranidipine.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/QO/C7QO00496F

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4. The Rearrangement of Allyl-Type Esters of β-Keto Acids

5. Deracemization of Quaternary Stereocenters by Pd-Catalyzed Enantioconvergent Decarboxylative Allylation of Racemic β-Ketoesters

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