Characterization of GvgD and GvgH encoded in the biosynthetic gene cluster of 4-formylaminooxyvinylglycine-Reference-Cited by-同舟云学术

Characterization of GvgD and GvgH encoded in the biosynthetic gene cluster of 4-formylaminooxyvinylglycine

Published:2023 Issue:11 Volume:10 Page:2782-2789
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Pang Linlin¹^ORCID,Niu Weijing¹,Duan Yuwei¹,Bian Xiaoying¹^ORCID,Zhang Youming¹²,Zhong Guannan¹³^ORCID

Affiliation:

1. Helmholtz International Laboratory for AntiInfectives, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China

2. CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology and Faculty of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China

3. Suzhou Research Institute of Shandong University, Suzhou 215123, China

Abstract

We report that GvgD catalyzes a reversible amidinylation ofl-canaline and GvgH installs the aminooxy groupviaγ-elimination and addition.

Funder

Natural Science Foundation of Jiangsu Province

Fundamental Research Fund of Shandong University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00007A

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