A cost-effective smartphone-based device for rapid C-reaction protein (CRP) detection using magnetoelastic immunosensor

Author:

Yuan Zhongyun12ORCID,Han Mengshu12,Li Donghao12,Hao Runfang12,Guo Xing12,Sang Shengbo12,Zhang Hongpeng3,Ma Xingyi4ORCID,Jin Hu5,Xing Zhijin6,Zhao Chun7

Affiliation:

1. Shanxi Key Laboratory of Micro Nano Sensors & Artificial Intelligence Perception, College of Information and Computer, Taiyuan University of Technology, Taiyuan, 030024, China

2. Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education, Taiyuan University of Technology, Taiyuan, 030024, China

3. Department of Vascular Surgery, Chinese PLA General Hospital, 100853, Beijing, China

4. School of Science, Harbin Institute of Technology, Shenzhen, Guangdong 518055, China

5. Division of Electrical Engineering, Hanyang University, 15588 Ansan, Republic of Korea

6. Department of Ultrasound Medicine, Shenzhen Hospital of the University of Hong Kong, 518053, Shenzhen, China

7. College of Information and Communication Engineering, Sungkyunkwan University, Chunchun-Dong, Changan-Ku, 440746 Suwon, Republic of Korea

Abstract

A smartphone-based C-reaction protein magnetoelastic (CRP-ME) immunosensor was developed. In this study, CRP can be detected with a sensitivity of 12.90 Hz μg−1 mL−1 and detection limit of 2.349 × 10−4 μg mL−1.

Funder

National Natural Science Foundation of China

International Science and Technology Cooperation Program of Shanxi Province

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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