N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea: a privileged motif for catalyst development

Author:

Zhang Zhiguo1234,Bao Zongbi1234,Xing Huabin1234

Affiliation:

1. Key Laboratory of Biomass Chemical Engineering of Ministry of Education

2. Department of Chemical and Biological Engineering

3. Zhejiang University

4. Hangzhou 310027, China

Abstract

This review summarizes the key developments of N,N′-bis[3,5-bis(trifluoromethyl)phenyl]thiourea (Schreiner's thiourea)-mediated reactions with the aim to further expand the applications of (thio)urea-based catalysts.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference63 articles.

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2. M. Kotke and P. R.Schreiner , in Hydrogen Bonding in Organic Synthesis , ed. P. M. Pihko , Wiley-VCH Verlag GmbH & Co. KGaA , Weinheim , 2009 , pp. 141–351

3. K. Hof and K. M.Lippert and P. R.Schreiner , in Science of Synthesis – Asymmetric Organocatalysis , ed. K. Maruoka , Thieme , Stuttgart , 2011 , pp. 297–412

4. Hydrogen-Bond-Mediated Asymmetric Catalysis

5. Small-Molecule H-Bond Donors in Asymmetric Catalysis

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