Evaluation of fully-functionalized diazirine tags for chemical proteomic applications
Author:
Affiliation:
1. Department of Chemistry
2. The Scripps Research Institute
3. Jupiter
4. USA
5. Research and Development
6. Bristol Myers Squibb Company
7. Princeton
Abstract
The chemical proteomic properties of five diazirine-based, fully-functionalized photoaffinity tags, including a newly developed, minimal tag, were compared. This study provides guidance for the development of new photoaffinity probes.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC01360B
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