Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

Author:

Sherin Peter S.12345ORCID,López-Duarte Ismael6789ORCID,Dent Michael R.6789,Kubánková Markéta6789ORCID,Vyšniauskas Aurimas6789ORCID,Bull James A.6789ORCID,Reshetnikova Evdokiya S.1023ORCID,Klymchenko Andrey S.1112131415ORCID,Tsentalovich Yuri P.12345ORCID,Kuimova Marina K.6789ORCID

Affiliation:

1. International Tomography Center SB RAS

2. Novosibirsk

3. Russia

4. Department of Natural Sciences

5. Novosibirsk State University

6. Department of Chemistry

7. Imperial College London

8. London

9. UK

10. Institute of Molecular and Cellular Biology SB RAS

11. Laboratoire de Biophotonique et Pharmacologie

12. UMR 7213 CNRS

13. Faculté de Pharmacie

14. Université de Strasbourg

15. 67401 ILLKIRCH Cedex

Abstract

Using fluorescent probes, we demonstrate that the plasma membrane of porcine eye lens fiber cells displays an unprecedentedly high degree of lipid ordering.

Funder

Royal Society of Chemistry

Engineering and Physical Sciences Research Council

Imperial College London

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference40 articles.

1. A. van Leeuwenhoek , The Collected Letters of Antoni van Leeuwenhoek, letter no. 81, english, July 25, 1684, Swets Zeitlinger, Amsterdam, 1952, vol. IV, pp. 253–299

2. Duane’s Ophthalmology, ed. W. Tasman and E. A. Jaeger, Williams & Wilkins, Philadelphia, USA, 2007, ch. 15

3. Cell contacts in human and bovine lenses

4. Gap junctions of chick lens fiber cells

5. Ageing and vision: structure, stability and function of lens crystallins

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