Manipulating the helix–coil transition profile of synthetic polypeptides by leveraging side-chain molecular interactions
Author:
Affiliation:
1. Department of Materials Science and Engineering
2. University of Illinois at Urbana–Champaign
3. Urbana
4. USA
5. Department of Chemistry
6. University of Illinois at Urbana-Champaign
7. MilliporeSigma
8. St. Louis
Abstract
Based on the pH-sensitive, conformationally tunable triazole polypeptides, we reported the manipulation of helix–coil transition profile determined by the leveraging interactions of the triazole and other side-chain helix-influencing ligands.
Funder
Division of Chemistry
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2020/PY/C9PY01857C
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