Development of Ru-polypyridyl complexes for real-time monitoring of Aβ oligomers and inhibition of Aβ fibril formation-Reference-Cited by-同舟云学术

Development of Ru-polypyridyl complexes for real-time monitoring of Aβ oligomers and inhibition of Aβ fibril formation

Published:2024 Issue:6 Volume:12 Page:1449-1453
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Chen Xian¹,Wang Jiaoyang¹,Mo Zhenzhuo¹,Han Lu¹,Cheng Kaiqing¹,Xie Cheng²,Liu Genyan²,Jiang Lijun³,Wang Kai¹,Pan Jie¹^ORCID

Affiliation:

1. College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China

2. Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, PR China

3. College of Life Sciences, Central China Normal University, Wuhan 430062, P. R. China

Abstract

Two Ru complexes, Ru-WJ and Ru-YH, were designed and synthesized to detect Aβ aggregates at an early AD stage. Ru-WJ and Ru-YH could quickly cross the BBB of young AD mice. Ru-YH can also inhibit the growth of Aβ.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D3BM01929B

Reference30 articles.

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