Host–guest binding between cucurbit[8]uril and amphiphilic peptides achieved tunable supramolecular aggregates for cancer diagnosis-Reference-Cited by-同舟云学术

Host–guest binding between cucurbit[8]uril and amphiphilic peptides achieved tunable supramolecular aggregates for cancer diagnosis

Published:2024 Issue:34 Volume:15 Page:13779-13787
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Niu Jie¹,Yu Jie¹,Wu Xuan²,Zhang Ying-Ming¹,Chen Yong¹,Yu Zhilin³^ORCID,Liu Yu¹^ORCID

Affiliation:

1. College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China

2. School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, P. R. China

3. Key Laboratory of Functional Polymer Materials, Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, P. R. China

Abstract

An oxidation-driven supramolecular aggregate constructed by cucurbituril, perylene imide, and methionine peptide, displays tunable morphology conversion in cancer cells, achieving targeted imaging, endoplasmic reticulum dysfunction, and cell death.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin Municipality

Fundamental Research Funds for the Central Universities

Nankai University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC04261A

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