Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential-Reference-Cited by-同舟云学术

Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential

Published:2024 Issue: Volume: Page:
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Pierre Herma C.¹,Amrine Chiraz Soumia M.¹²,Doyle Michael G.¹,Salvi Amrita³,Raja Huzefa A.¹^ORCID,Chekan Jonathan R.¹^ORCID,Huntsman Andrew C.⁴,Fuchs James R.⁴^ORCID,Liu Kebin⁵⁶^ORCID,Burdette Joanna E.³^ORCID,Pearce Cedric J.⁷,Oberlies Nicholas H.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, P.O. Box 26170, Greensboro, North Carolina 27402, USA

2. Department of Physical and Earth Sciences. Arkansas Tech University, 1701 N. Boulder Ave., Russellville, Arkansas 72801, USA

3. Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave (M/C 870), Chicago, Illinois 60607, USA

4. Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, USA

5. Department of Biochemistry and Molecular Biology and the Georgia Cancer Center, Medical College of Georgia, Augusta, GA 30912, USA

6. Charlie Norwood Veterans Affairs Medical Center, Augusta, GA 30904, USA

7. Mycosynthetix, Inc., Hillsborough, NC, 27278, USA

Abstract

Verticillin A has a beautiful and complex scaffold, as noted in this image of the crystal structure. This review encapsulates both the >50 year history of verticillins and the exciting studies that have been carried out recently, offering insights and opportunities for future research.

Funder

National Cancer Institute

National Center for Complementary and Integrative Health

Medicinal Chemistry Division, American Chemical Society

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NP/D3NP00068K

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