Guanidine hydrochloride (GuHCl)-catalysed microwave-mediated solvent- and metal-free synthesis of pyrimido[1,2-<i>a</i>]benzimidazole from aryl aldehyde and aryl methyl ketone-Reference-Cited by-同舟云学术

Guanidine hydrochloride (GuHCl)-catalysed microwave-mediated solvent- and metal-free synthesis of pyrimido[1,2-a]benzimidazole from aryl aldehyde and aryl methyl ketone

Published:2024 Issue:16 Volume:26 Page:9230-9240
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Jagdale Rushikant¹,Hussain Mohammad Zahid¹,Goswami Koushik²,Peraman Ramalingam¹,Jana Anupam¹^ORCID

Affiliation:

1. Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Hajipur, Hajipur, Bihar–844102, India

2. Department of Chemistry, Amity University Kolkata, Rajarhat, New Town, Kolkata 700135, India

Abstract

The rapid, eco-friendly, solvent- and metal-free microwave-assisted synthesis of pyrimido[1,2-a]benzimidazole in high yields was achieved using the green organocatalyst guanidine hydrochloride using simple and inexpensive starting materials.

Funder

Science and Engineering Research Board

National Institute of Pharmaceutical Education & Research

Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC01363H

Reference41 articles.

1. Synthesis and Antibacterial Activity of Some Imidazo(1,2-a)pyrimidine Derivatives.

2. Synthesis and antimicrobial activity of certain imidazo[1,2-a]pyrimidines

3. Antifungal activity in vitro of some imidazo[1,2-a]pyrimidine derivatives

4. Exploratory Investigations Probing a Preparatively Versatile, Pyridinium Salt Photoelectrocyclization−Solvolytic Aziridine Ring Opening Sequence

5. Analogs of WIN 62,577 Define a Second Allosteric Site on Muscarinic Receptors