Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS-Reference-Cited by-同舟云学术

Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS

Published:2015 Issue:10 Volume:140 Page:3565-3572
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Diéguez L.¹²³,Winter M. A.¹²³,Pocock K. J.¹²³,Bremmell K. E.⁴²⁵³,Thierry B.¹²³

Affiliation:

1. Ian Wark Research Institute

2. University of South Australia

3. Australia

4. School of Pharmacy and Medical Sciences

5. Adelaide

Abstract

Depletion of >99.7% WBCs enabling tumor cell recovery from blood with nano-rough PDMS microfluidic negative enrichment devices functionalised with anti-CD45.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AN/C4AN01768D

Reference29 articles.

1. Molecular analysis of circulating tumour cells—biology and biomarkers

2. Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data

3. Isolation of rare circulating tumour cells in cancer patients by microchip technology

4. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

5. Advances and critical concerns with the microfluidic enrichments of circulating tumor cells

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