Radical trideuteromethylation with deuterated dimethyl sulfoxide in the synthesis of heterocycles and labelled building blocks-Reference-Cited by-同舟云学术

Radical trideuteromethylation with deuterated dimethyl sulfoxide in the synthesis of heterocycles and labelled building blocks

Published:2016 Issue:84 Volume:52 Page:12486-12489
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Caporaso Roberta¹²³⁴⁵,Manna Srimanta¹²³⁴⁵,Zinken Sarah¹²³⁴⁵,Kochnev Alexander R.⁶⁷⁸⁹¹⁰,Lukyanenko Evgeny R.⁶⁷⁸⁹¹⁰,Kurkin Alexander V.⁶⁷⁸⁹¹⁰,Antonchick Andrey P.¹²³⁴⁵

Affiliation:

1. Chemical Biology

2. Max Planck Institute of Molecular Physiology

3. Otto-Hahn-Straβe 11

4. 44227 Dortmund

5. Germany

6. Department of Chemistry

7. Lomonosov Moscow State University

8. 1/3 Leninskie Gory

9. 119991 Moscow

10. Russia

Abstract

A selective introduction of trideuteromethyl groups for the synthesis of labelled compounds under radical reaction conditions is demonstrated.

Funder

Max-Planck-Gesellschaft

Università di Bologna

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07196A

Reference61 articles.

1. Using Deuterium in Drug Discovery: Leaving the Label in the Drug

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3. Secondary kinetic isotope effects involving deuterated nucleophiles

4. Deuterium magnetic resonance, applications in chemistry, physics and biology

5. Studies with Deuterated Drugs

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