BrSPR-20-P1 peptide isolated from Brevibacillus sp. developed into liposomal hydrogel as a potential topical antimicrobial agent

Author:

Changsan Narumon1ORCID,Atipairin Apichart23ORCID,Sakdiset Pajaree23ORCID,Muenraya Poowadon23ORCID,Balekar Neelam4,Srichana Teerapol5ORCID,Sritharadol Rutthapol6,Phanapithakkun Suranate23ORCID,Sawatdee Somchai23ORCID

Affiliation:

1. College of Pharmacy, Rangsit University, Pathumtani, 12000, Thailand

2. School of Pharmacy, Walailak University, Thasala, Nakhon Si Thammarat, 80160, Thailand

3. Drug and Cosmetics Excellence Center, Walailak University, Thasala, Nakhon Si Thammarat, 80160, Thailand

4. College of Pharmacy, IPS Academy, Indore, Madhya Pradesh, 452012, India

5. Drug Delivery System Excellence Center, Department of Pharmaceutical Technology Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand

6. Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phaya Thai Road, Pathum Wan, Bangkok, 10330, Thailand

Abstract

BrSPR-20-P1 antimicrobial peptide (P1-AMP) is a novel antimicrobial peptide isolated from Brevibacillus sp. SPR-20 and has been developed as a liposomal in chitosan hydrogel. It has potential to be used as a topical antimicrobial agent.

Funder

Walailak University

Publisher

Royal Society of Chemistry (RSC)

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