Base-catalyzed multicomponent access to quinoxalin-2-thiones from <i>o</i>-phenylenediamines, aryl ketones and sulfur-Reference-Cited by-同舟云学术

Base-catalyzed multicomponent access to quinoxalin-2-thiones from o-phenylenediamines, aryl ketones and sulfur

Published:2022 Issue:36 Volume:20 Page:7226-7231
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Nguyen Thanh Binh¹^ORCID,Mac Dinh Hung²,Tran Thi Minh Chau²,Nguyen Bich Ngoc²³,Cao Hai Thuong³

Affiliation:

1. Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Université Paris-Sud, Université Paris-Saclay, 1, av de la Terrasse, 91198 Gif-sur-Yvette, France

2. Faculty of chemistry, VNU University of Science, Vietnam National University in Hanoi, 19 Le Thanh Tong, Hanoi, Viet Nam

3. Le Quy Don Technical University, 236 Hoang Quoc Viet, Ha Noi, Vietnam

Abstract

Quinoxalin-2-thiones were readily synthesized from o-phenylenediamines, ketones and sulfur. The reactions proceeded under simple and mild conditions with chromatography-free purification and were amenable to large-scale synthesis.

Funder

University of Science, Vietnam National University, Hanoi

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01343F

Reference30 articles.

1. Q39, a novel synthetic Quinoxaline 1,4-Di-N-oxide compound with anti-cancer activity in hypoxia

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3. Perturbing pro-survival proteins using quinoxaline derivatives: A structure–activity relationship study

4. Novel Quinoxaline-Based Organic Sensitizers for Dye-Sensitized Solar Cells

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