Catalytic stereoselective synthesis of cyclopentanones from donor–acceptor cyclopropanes and <i>in situ</i>-generated ketenes-Reference-Cited by-同舟云学术

Catalytic stereoselective synthesis of cyclopentanones from donor–acceptor cyclopropanes and in situ-generated ketenes

Published:2024 Issue:35 Volume:22 Page:7128-7132
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mitra Shubhanjan¹,Connolly Sophie M.¹,Ayidi Saud¹,Mondal Mukulesh²,Panda Manashi²,Kelly Brian G.³,Kerrigan Nessan J.¹^ORCID

Affiliation:

1. School of Chemical Sciences and Life Sciences Institute, Dublin City University, Glasnevin, Dublin 9, Ireland

2. Department of Chemistry, Oakland University, 2200 N. Squirrel Rd, MI 48309, USA

3. KelAda Pharmachem, Belfield, Dublin 4, Ireland

Abstract

Diastereoselective and enantiospecific (3 + 2)-cycloaddition of in situ-generated ketenes with donor–acceptor cyclopropanes to give cyclopentanones is realised.

Funder

Irish Research Council

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB01313A

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