Fluorofenidone-loaded PLGA microspheres for targeted treatment of paraquat-induced acute lung injury in rats-Reference-Cited by-同舟云学术

Fluorofenidone-loaded PLGA microspheres for targeted treatment of paraquat-induced acute lung injury in rats

Published:2015 Issue:38 Volume:5 Page:30153-30159
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tang Jing¹²³⁴⁵,Liu Zhenbao⁶⁷⁸⁵,Zhang Yue⁶⁷⁸⁵,Wang Ling¹²³⁴⁵,Li Dai⁹⁷¹⁰⁵,Ding Jinsong⁶⁷⁸⁵,Jiang Xuehua¹²³⁴⁵

Affiliation:

1. Key Laboratory of Drug Targeting and Drug Delivery System

2. West China School of Pharmacy

3. Sichuan University

4. Chengdu 610041

5. PR China

6. School of Pharmaceutical Sciences

7. Central South University

8. Changsha 410013

9. Xiangya Hospital

10. Changsha 410008

Abstract

Lung-targeting fluorofenidone (AKF) loaded PLGA microspheres (AKF-MS) for the treatment of paraquat (PQ)-induced acute lung injury in rats, were constructed by a solvent evaporation method.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA00656B

Reference33 articles.

1. Paraquat in Developing Countries

2. Methylene blue protects against paraquat-induced acute lung injury in rats

3. Protective effects of N-acetylcysteine treatment post acute paraquat intoxication in rats and in human lung epithelial cells

4. Role of antioxidants in paraquat toxicity

5. Medical management of paraquat ingestion

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