Organ-on-a-chip: the next generation platform for risk assessment of radiobiology

Author:

Quan Yi1234,Sun Miao56784,Tan Zhaoyi1234,Eijkel Jan C. T.9101112,van den Berg Albert9101112ORCID,van der Meer Andries131112ORCID,Xie Yanbo56784ORCID

Affiliation:

1. Institute of Nuclear Physics and Chemistry

2. China Academy of Engineering Physics (CAEP)

3. Mianyang

4. China

5. Joint Laboratory of Nanofluidics and Interfaces

6. School of Physical and Technology

7. Northwestern Polytechnical University

8. Xi'an

9. BIOS, Lab on a Chip Group

10. MESA+ Institution for Nanotechnology

11. University of Twente

12. The Netherlands

13. Department of Applied Stem Cell Technologies

Abstract

Organ-on-a-chip technology has great potential for the next generation risk estimation of low dose internal irradiation, due to its success in mimicking human organs/tissues, which possibly can significantly improve on current animal models.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

China Academy of Engineering Physics

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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