Enzymatically degradable, starch-based layer-by-layer films: application to cytocompatible single-cell nanoencapsulation

Author:

Moon Hee Chul12345,Han Sol12345,Borges João26789,Pesqueira Tamagno26789,Choi Hyunwoo12345,Han Sang Yeong12345,Cho Hyeoncheol12345,Park Ji Hun1011125,Mano João F.26789ORCID,Choi Insung S.12345ORCID

Affiliation:

1. Center for Cell-Encapsulation Research

2. Department of Chemistry

3. KAIST

4. Daejeon 34141

5. Korea

6. CICECO-Aveiro Institute of Materials

7. University of Aveiro

8. Campus Universitário de Santiago

9. 3810-193 Aveiro

10. Department of Science Education

11. Ewha Womans University

12. Seoul 03760

Abstract

Starch-based layer-by-layer (LbL) nanofilms are formed and enzymatically degraded on individual Saccharomyces cerevisiae in a highly cytocompatible fashion. Their enzymatic degradation by α-amylase is also exploited for the controlled release of DNA.

Funder

National Research Foundation of Korea

Ministério da Ciência, Tecnologia e Ensino Superior

H2020 European Research Council

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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