On the influence of water molecules on the outer electronic shells of R–SeH, R–Se(−) and R–SeOH fragments in the selenocysteine amino acid residue
Author:
Affiliation:
1. Institute of Chemistry
2. Saint Petersburg State University
3. Saint Petersburg
4. Russia
Abstract
The presence of water molecules near the selenocysteine residue in the active centre of the GPx enzyme promotes its antioxidant activity. The 77Se NMR chemical shift is sensitive both to the oxidation and the hydration states of the selenium atom.
Funder
Russian Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP01345A
Reference44 articles.
1. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
2. Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?
3. Selenocysteine robustness versus cysteine versatility: a hypothesis on the evolution of the moonlighting behaviour of peroxiredoxins
4. T. Nauser , D.Steinmann and W. H.Koppenol , Amino Acids , Springer , 2012 , vol. 42, pp. 39–44
5. Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Unveiling the electronic structure peculiarities of phosphine selenides as NMR probes for non-covalent interactions: an experimental and theoretical study;Physical Chemistry Chemical Physics;2024
2. Non-covalent interactions in the glutathione peroxidase active center and their influence on the enzyme activity;Organic & Biomolecular Chemistry;2022
3. Hydration of selenolate moiety: Ab initio investigation of properties of O–H⋯Se(–) hydrogen bonds in CH 3 Se (–)⋯( H 2 O ) n clusters;Journal of Computational Chemistry;2021-08-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3