Label-free detection of DNA hybridization with a compact LSPR-based fiber-optic sensor

Author:

Kaye Savannah1234,Zeng Zheng56784,Sanders Mollye1234,Chittur Krishnan9103411,Koelle Paula M.1134,Lindquist Robert1234,Manne Upender12134,Lin Yongbin1234,Wei Jianjun56784ORCID

Affiliation:

1. Center for Applied Optics

2. University of Alabama at Huntsville

3. Huntsville

4. USA

5. Department of Nanoscience

6. Joint School of Nanoscience and Nanoengineering

7. University of North Carolina at Greensboro

8. Greensboro

9. Chemical and Materials Engineering

10. University of Alabama Huntsville

11. Genecapture

12. Department of Pathology

13. University of Alabama at Birmingham

Abstract

A miniaturized, robust, localized surface plasmon resonance (LSPR)–coupled fiber-optic (FO) nanoprobe providing an integrated and portable solution for detection of DNA hybridization and measurement of DNA concentrations has been demonstrated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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