Metal-free synthesis of 3,5-disubstituted 1H- and 1-aryl-1H-pyrazoles from 1,3-diyne-indole derivatives employing two successive hydroaminations-Reference-Cited by-同舟云学术

Metal-free synthesis of 3,5-disubstituted 1H- and 1-aryl-1H-pyrazoles from 1,3-diyne-indole derivatives employing two successive hydroaminations

Published:2015 Issue:27 Volume:5 Page:21112-21124
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Bassaco Mariana M.¹²³⁴,Fortes Margiani P.¹²³⁴,Kaufman Teodoro S.⁵⁶⁷,Silveira Claudio C.¹²³⁴

Affiliation:

1. Departamento de Química

2. Universidade Federal de Santa Maria

3. Santa Maria

4. Brazil

5. Instituto de Química Rosario (CONICET-UNR)

6. Rosario

7. Argentina

Abstract

The uncatalyzed synthesis of 3,5-disubstituted 1H- and 1-aryl-1H-pyrazoles derived from 1,3-diyne indoles was successfully carried out in PEG 400. The scope and limitations of the reaction were studied.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA16439C

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