Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown-Reference-Cited by-同舟云学术

Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown

Published:2020 Issue:66 Volume:56 Page:9477-9480
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Kim Beob Soo¹²³⁴⁵^ORCID,Naito Mitsuru⁶⁷³⁸⁵^ORCID,Kamegawa Rimpei¹²³⁴⁵,Kim Hyun Jin⁶⁷³⁸⁵^ORCID,Iizuka Ryo⁹³⁸⁵,Funatsu Takashi⁹³⁸⁵,Ueno Shingo¹⁰¹¹¹²⁵,Ichiki Takanori¹²³⁴⁵,Kishimura Akihiro¹³¹⁴¹⁵⁵,Miyata Kanjiro¹²³⁴⁵^ORCID

Affiliation:

1. Department of Materials Engineering

2. Graduate School of Engineering

3. The University of Tokyo

4. Tokyo 113-8656

5. Japan

6. Center for Disease Biology and Integrative Medicine

7. Graduate School of Medicine

8. Tokyo 113-0033

9. Graduate School of Pharmaceutical Sciences

10. Innovation Center of NanoMedicine

11. Kawasaki Institute of Inductrial Promotion

12. Kawasaki 210-0821

13. Center for Molecular Systems

14. Kyushu University

15. Fukuoka 819-0395

Abstract

A photo-responsive nanovesicle (PROsome) is fabricated via polyion complex between PEG-polypeptides and photo-reactive/antisense oligodeoxynucleotides (PROs/ASOs), eliciting the switchable stability for efficient cellular uptake and gene knockdown.

Funder

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC01750G

Reference23 articles.

1. Polymeric Vesicles: From Drug Carriers to Nanoreactors and Artificial Organelles

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