Cyclopentane rings in hydrophobic chains of a phospholipid enhance the bilayer stability to electric breakdown

Author:

Batishchev Oleg V.1234ORCID,Alekseeva Anna S.5234ORCID,Tretiakova Daria S.5234ORCID,Galimzyanov Timur R.12346ORCID,Chernyadyev Andrey Yu.1234ORCID,Onishchenko Natalia R.5234ORCID,Volynsky Pavel E.5234ORCID,Boldyrev Ivan A.5234ORCID

Affiliation:

1. Frumkin Institute of Physical Chemistry and Electrochemistry

2. Russian Academy of Sciences

3. Moscow

4. Russia

5. Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

6. National University of Science and Technology MISiS

Abstract

Bilayers of a phospholipid with cyclopentane-containing chains are stable to pore formation due to restricted conformational mobility of the chains and inability of the molecules to rearrange in order to line the edge of a hydrophilic pore.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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