Anticancer activity of ruthenium and osmium cyclometalated compounds: identification of ABCB1 and EGFR as resistance mechanisms-Reference-Cited by-同舟云学术

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Anticancer activity of ruthenium and osmium cyclometalated compounds: identification of ABCB1 and EGFR as resistance mechanisms

Published:2020 Issue:3 Volume:7 Page:678-688
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Licona Cynthia¹²³⁴⁵,Delhorme Jean-Baptiste¹²³⁴⁵,Riegel Gilles¹²³⁴⁵,Vidimar Vania¹²³⁴⁵,Cerón-Camacho Ricardo⁶⁷⁸⁹¹⁰,Boff Bastien¹¹¹²¹³¹⁴⁵,Venkatasamy Aina¹²³⁴⁵^ORCID,Tomasetto Catherine¹⁵²¹⁶¹⁷⁵,da Silva Figueiredo Celestino Gomes Priscila¹⁸¹⁹²⁰⁵,Rognan Didier¹⁸¹⁹²⁰⁵^ORCID,Freund Jean-Noel¹²³⁴⁵^ORCID,Le Lagadec Ronan⁶⁷⁸⁹¹⁰^ORCID,Pfeffer Michel¹¹¹²¹³¹⁴⁵^ORCID,Gross Isabelle¹²³⁴⁵^ORCID,Mellitzer Georg¹²³⁴⁵^ORCID,Gaiddon Christian¹²³⁴⁵^ORCID

Affiliation:

1. Interface Recherche Fondamentale en Cancérologie

2. Université de Strasbourg

3. Inserm UMR_S 1113

4. Strasbourg

5. France

6. Instituto de Química

7. UNAM

8. Circuito Exterior s/n

9. Ciudad Universitaria

10. Ciudad de México

11. Institut de Chimie

12. UMR7177

13. Laboratoire de Synthèses Métallo-Induites

14. 4 rue Blaise Pascal

15. IGBMC

16. U1258 INSERM UMR-7104 CNRS

17. Ilkirch

18. Laboratoire d'Innovation Thérapeutique

19. UMR7200 CNRS-Université de Strasbourg

20. F-67400 Illkirch

Abstract

Switching from ruthenium to osmium reduces sensitivity towards ABCB1 resistance for cyclometalated anticancer drugs.

Funder

Centre National de la Recherche Scientifique

Ligue Contre le Cancer

Association pour la Recherche sur le Cancer

European Cooperation in Science and Technology

Universidad Nacional Autónoma de México

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QI/C9QI01148J

Reference46 articles.

1. Antitumour metal compounds: more than theme and variations

2. The resurgence of platinum-based cancer chemotherapy

3. Organometallic Anticancer Compounds

4. Approaching tumour therapy beyond platinum drugs

5. Development of anticancer agents: wizardry with osmium

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