Regioselective catalytic asymmetric N-alkylation of isoxazol-5-ones with para-quinone methides-Reference-Cited by-同舟云学术

Regioselective catalytic asymmetric N-alkylation of isoxazol-5-ones with para-quinone methides

Published:2020 Issue:13 Volume:18 Page:2398-2404
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Qi Suo-Suo¹²³⁴⁵,Jiang Zhen-Hui¹²³⁴⁵,Chu Ming-Ming¹²³⁴⁵,Wang Yi-Feng¹²³⁴⁵^ORCID,Chen Xue-Yang¹²³⁴⁵,Ju Wan-Zhen¹²³⁴⁵,Xu Dan-Qian¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology

2. Key Laboratory of Green Pesticides and Cleaner Production Technology of Zhejiang Province

3. Department of Green Chemistry and Technology

4. Zhejiang University of Technology

5. Hangzhou 310014

Abstract

A highly regioselective and enantioselective N-alkylation of isoxazol-5-ones with para-quinone methides has been developed to obtain enantioenriched N-diarylmethane substituted isoxazolinones with high yields and enantioselectivities.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00393J

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