The good, the bad, and the ugly – controlling singlet oxygen through design of photosensitizers and delivery systems for photodynamic therapy

Author:

Callaghan Susan12345ORCID,Senge Mathias O.12345ORCID

Affiliation:

1. School of Chemistry

2. SFI Tetrapyrrole Laboratory

3. Trinity Biomedical Sciences Institute

4. Trinity College Dublin

5. the University of Dublin

Abstract

To afford effective photosensitizers and delivery systems for photodynamic therapy their design phase must consider all aspects of singlet oxygen. This perspective highlights that progression of this field is dependent on the control and modulation of its star, singlet oxygen.

Funder

Science Foundation Ireland

Irish Research Council for Science, Engineering and Technology

H2020 Marie Skłodowska-Curie Actions

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Reference196 articles.

1. N. R. Finsen , La Photothérapie , Georges Carré et C. Naud , Paris , 1899

2. H. von Tappeiner and A.Jodlbauer , Die sensibilisierende Wirkung fluorescierender Substanzen; gesammelte Untersuchungen über die photodynamische Erscheinung , Vogel , Leipzig , 1907

3. A. Jesionek , Lichtbiologie. Die experimentellen Grundlagen der modernen Lichtbehandlung , Vieweg , Braunschweig , 1910

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