Welsh onion extract inhibits PCSK9 expression contributing to the maintenance of the LDLR level under lipid depletion conditions of HepG2 cells-Reference-Cited by-同舟云学术

Welsh onion extract inhibits PCSK9 expression contributing to the maintenance of the LDLR level under lipid depletion conditions of HepG2 cells

Author:

Choi Hyo-Kyoung¹²³,Hwang Jin-Taek¹²³⁴⁵,Nam Tae-Gyu¹²³,Kim Sung Hee¹²³,Min Dong-Kook⁶⁷⁸⁹¹⁰,Park Sahng Wook⁶⁷⁸⁹¹⁰,Chung Min-Yu¹²³^ORCID

Affiliation:

1. Korea Food Research Institute

2. Seongnam City

3. Republic of Korea

4. Department of Food Biotechnology

5. Korea University of Science & Technology

6. Department of Biochemistry and Molecular Biology

7. Institute of Genetic Science

8. Integrated Genomic Research Center for Metabolic Regulation

9. Yonsei University College of Medicine

10. Seoul

Abstract

Statins mediate the transactivation of PCSK9, which in turn limits their cholesterol-lowering effects via LDL receptor (LDLR) degradation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

Reference38 articles.

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