Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides-Reference-Cited by-同舟云学术

Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides

Published:2019 Issue:14 Volume:6 Page:2324-2328
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu He¹²³⁴⁵,Shen Qilong¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Organofluorine Chemistry

2. Center for Excellence in Molecular Synthesis

3. Shanghai Institute of Organic Chemistry

4. University of Chinese Academy Sciences

5. Chinese Academy of Sciences

Abstract

The synthesis and characterization of a bistrifluoromethylated organocuprate [Ph₄P]⁺[Cu(CF₃)₂]⁻ and its reactions with a variety of activated heteroaryl bromides, chlorides and iodides were described.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00527G

Reference31 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in medicinal chemistry