Metabolic glycan labeling-assisted discovery of cell-surface markers for primary neural stem and progenitor cells

Author:

Bai Qing-Ran12345,Dong Lu678910,Hao Yi678910,Chen Xing678910ORCID,Shen Qin111213145ORCID

Affiliation:

1. PTN Graduate Program

2. School of Life Sciences

3. Tsinghua University

4. Beijing 100084

5. China

6. College of Chemistry and Molecular Engineering

7. Peking-Tsinghua Center for Life Sciences

8. Beijing National Laboratory for Molecular Sciences

9. Synthetic and Functional Biomolecules Center, and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education

10. Peking University

11. Brain and Spinal Cord Innovative Research Center of Tongji Hospital

12. School of Life Sciences and Technology

13. Tongji University

14. Shanghai 200065

Abstract

Metabolic labeling with azidosugars in a neural stem cell (NSC)-enriched endothelial coculture followed by mass-spectrometry profiling identifies sialoglycoproteins on NSCs.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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