Solventless and metal-free regioselective hydrofluorination of functionalized alkynes and allenes: an efficient protocol for the synthesis of gem-difluorides-Reference-Cited by-同舟云学术

Solventless and metal-free regioselective hydrofluorination of functionalized alkynes and allenes: an efficient protocol for the synthesis of gem-difluorides

Published:2019 Issue:6 Volume:21 Page:1467-1471
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Lu Zhichao¹²³⁴^ORCID,Bajwa Bhvandip S.¹⁵⁶⁴,Liu Shiwen⁷⁸⁹¹⁰¹¹,Lee Sheye¹⁵⁶⁴^ORCID,Hammond Gerald B.¹²³⁴^ORCID,Xu Bo⁷⁸⁹¹⁰¹¹^ORCID

Affiliation:

1. Department of Chemistry

2. University of Louisville

3. Louisville

4. USA

5. California State University

6. Fresno

7. Key Laboratory of Science and Technology of Eco-Textiles

8. Ministry of Education

9. College of Chemistry

10. Chemical Engineering and Biotechnology

11. Donghua University

Abstract

A highly acidic fluorination system generated by DMPU-12HF and KHSO₄-13HF can facilitate exclusive Markovnikov addition of HF to widely functionalized alkynes and allenes to produce gem-difluorides with an easy workup.

Funder

National Natural Science Foundation of China

Camille and Henry Dreyfus Foundation

California State University, Fresno

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/GC/C8GC03876G

Reference38 articles.