Current advance of CRISPR/Cas-based SERS technology

Author:

Wang Huimin12,Su Ailing1,Chang Jingjing2,Liu Xiangguo3,Liang Chongyang4ORCID,Xu Shuping156ORCID

Affiliation:

1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China

2. School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun 130022, P. R. China

3. Institute of Agricultural Biotechnology, Jilin Academy of Agricultural Sciences, Changchun, 130033, P. R. China

4. Institute of Frontier Medical Science, Jilin University, Changchun, 130021, P. R. China

5. Center for Supramolecular Chemical Biology, College of Chemistry, Jilin University, Changchun 130012, P. R. China

6. Theoretical Chemistry, College of Chemistry, Jilin University, Changchun 130012, P. R. China

Abstract

This review summarizes the applications of CRISPR/Cas technology combined with SERS for nucleic acid detection, the operation of CRISPR/Cas technology, elements of SERS sensors, and provides an outlook on future developments.

Funder

National Natural Science Foundation of China

Jilin University

Changchun Science and Technology Planning Project

Department of Science and Technology of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

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